Design and Fabrication of Dual Redox Responsive Nanoparticles with Diselenide Linkage Combined Photodynamically to Effectively Enhance Gene Expression

Yan Fang,1 Xiaojie Lin,2 Xuechao Jin,2 Dongjuan Yang,2 Shan Gao,2 Kai Shi,2 Mingshi Yang1,3 1Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, People’s Republic of China; 2Department of Pharmaceutics, School of Pharmaceutical Science, Shenyang Pharmaceutical University, Shenyang 117004, People’s Republic o

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Rural-urban comparisons of dengue seroprevalence in Malaysia

Abstract Background Each year an estimated 390 million dengue infections occur worldwide.In Malaysia, dengue is a growing public health concern but estimate of its disease burden remains uncertain.We compared the urban-rural difference of dengue seroprevalence and determined age-specific dengue seroprevalence in Malaysia.Methods We undertook analys

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Cryptogenic stroke. Part 2: paradoxical embolism

Cryptogenic stroke (CS) is defined as a subtype of stroke associated with a heterogeneous group of pathogenetic mechanisms that remained undetermined in the course of advanced diagnostic research.One third or fourth of the ischemic strokes is cryptogenic.Paradoxical embolism is considered the important cause of cryptogenic stroke and transient isch

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